Objective: To determine the efficacy and safety of OPTIC NERVE fenestration in patient with pseudotumor cerebri with visual loss despite medical treatment.
Design: Prospective; interventional case series.
Patients &Methods: 13 eyes of 13 patients with PTC and visual field loss resistant to medical treatment underwent OPTIC NERVE fenestration. Visual acuity, visual field, headache, intracranial pressures were checked before and after surgery. We defined visual field stability within 2db from mean deviation. OPTIC NERVE fenestration was performed with the patient under general anesthesia. A standard transconjunctival approach was used in all cases.
Results: After OPTIC NERVE fenestration visual field stabilized or improved in %85. Of 7 patients with acute papilledema, 6 patients improved, one patient worsened. Of 6 patients with chronic papilledema, 4 patients stabilized, one patient improved, one patient worsened. No significant difference was detected in MD (mean deviation) between operated eye from non operated eye after 1 week, 3 weeks, 2 months. The greatest improvement in visual field MD was detected between the first weeks to 3rd week after operation.
Conclusion: OPTIC NERVE fenestration effectively stabilizes or improves visual function in the majority of patient with pseudotumor cerebri and visual loss.